Sirtuins are a family of proteins that regulate cellular health. Sirtuins play a key role in regulating cellular homeostasis. Homeostasis involves keeping the cell in balance. However, sirtuins can only function in the presence of NAD+, nicotinamide adenine dinucleotide, a coenzyme found in all living cells.

NAD+, or nicotinamide adenine dinucleotide, is a critical coenzyme found in every cell in your body, and it’s involved in hundreds of metabolic processes — but NAD+ levels decline with age. NAD+ has two general sets of reactions in the human body: Helping turn nutrients into cellular energy as a key player in metabolism and working as a helper molecule for proteins that regulate other cellular functions. These processes are incredibly important.

This form of Vitamin B could be the key to increasing NAD+ levels — here’s why. Nicotinamide riboside is often called NR for short, and it’s a precursor to NAD+, meaning it's the raw material from which your body makes NAD+ through a series of chemical transformations. Human clinical studies, including ours, have shown efficacy of NR supplementation in increasing NAD+ levels.

Pterostilbene is a polyphenol, a type of molecule that occurs in plants, particularly small berries and nuts. Blueberries are a particularly rich source of pterostilbene; although it is found in grapes, pterostilbene (unlike its cousin resveratrol) doesn’t survive the wine-making process.

“Phenol” refers to a certain chemical structure (in this case, a hydroxyl group linked to a benzene ring); “poly” just means the molecules have more than one of the structure. One of polyphenols’ main jobs is to help the plant fight off pathogens. When eaten by humans, polyphenols may serve as powerful antioxidants.

Basis is designed to work beneath the surface, so its primary purpose is not to deliver surface-level results. Taking Basis is an investment in the long-term health of your cells, and you may not feel different despite the improvements happening inside your body. Everyone’s physiology is unique and results vary from person to person.

Elysium conducted a first-in-humans study demonstrating clearly that Basis can increase and sustain cellular NAD+ levels. Participants in the trial experienced a 40% average increase in cellular NAD+ levels within a month, which was maintained for the duration of the trial. We also tested a variety of biological markers to add to the existing body of evidence confirming that the ingredients in Basis are safe.

Our prepaid subscription plans are our most cost-effective options. When you select a semi-annual or annual plan, the pricing offers a savings to customers who commit to a long-term subscription. The longer the commitment, the greater the savings: $40/bottle for a 1-year (annual) subscription and $45/bottle for a 6-month (semi-annual) subscription. These prepaid subscriptions are considered final sale, so if you cancel in the middle of a 6-month or 1-year plan, you will continue to receive the remaining bottles, and the cancellation will take effect at the end of your plan before renewal. Our monthly subscriptions are $50/month and can be canceled at any time prior to your next shipment. Please contact our Customer Experience Team at care@elysiumhealth.com if you need to talk about your plan.

Mosaic, Basis, Signal, Matter, and Format are available in the United States and Canada. Vision, Index, and the Senolytic Complex are currently only available to ship and bill to addresses located in the U.S. Sign up for our newsletter to be notified of updates related to the international availability of our products.